Donepezil Brand Name, Interactions, Dosage And Pronunciation
Donepezil is a prescription medication that belongs to a class of drugs known as cholinesterase inhibitors. It can be used to treat Alzheimer’s disease and improve mental function and memory in patients. In the following 2-minute article, we discuss the brand names, interactions, dosage, warnings and pronunciation of donepezil.
What Is Donepezil?
Donepezil is a prescription medication that belongs to a class of drugs known as cholinesterase inhibitors.
Donepezil And Memantine
Donepezil may be used in conjunction with memantine to improve the treatment of dementia and Alzheimer’s.
To pronounce donepezil, sound out these syllables:
Dow - neh - puh - zil
Donepezil Mechanism Of Action
Donepezil binds and reversibly inactivates the cholinesterases, an enzyme that plays a role in Alzheimer’s disease. This increases acetylcholine concentrations at cholinergic synapses.
The uses of donepezil include the treatment of the following conditions:
- Alzheimer’s disease
- Poor mental function
- Other causes of memory loss
Donepezil Brand Names
The brand names of donepezil include the following:
- Aricept Evess
Side Effects Of Donepezil
Like most medications, donepezil does come with a list of associated side effects. Some of these symptoms are more severe and less common than others.
Common Side Effects
Most side effects of donepezil are relatively mild and should disappear within a few days. The most common side effects of this medication include the following:
- Loss of appetite
- Joint pain
- Muscle cramps
- Frequent urination
- Changes in behavior or mood
- Red, itching skin
If these side effects are mild, they should disappear within a few days. If side effects continue, talk to your doctor or another medical professional.
Serious Side Effects
Some side effects are serious and may require medical attention. If you are experiencing any of the following serious side effects, contact your doctor or pharmacist immediately. Call 911 if you think your symptoms are life threatening.
- Chest pain
- Slow heartbeat
- Pain when urinating
- Lower back pain
- Exceptionally high fever
- Bloody vomit
- New or worsening breathing problems
- Vomit that looks like coffee grounds
- Bruising of the skin
Disclaimer: Here at Manifest Pharmacy, our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who knows your medical history.
How To Take Donepezil
Take donepezil as directed by your doctor or other healthcare professional. Donepezil should be taken at bedtime unless you are otherwise directed. It may be taken with or without food, or on an empty stomach.
Swallow donepezil tablets whole, do not crush or chew them.
Your dosage of donepezil may vary depending on multiple factors, including the following:
- Your age
- Your weight
- Time of dosage
- Time between doses
- Number of doses you take each day
Dosage For Mild-to-Moderate Alzheimer’s Disease
Adult: 5mg taken once at bedtime. Your doctor may increase dosage as needed.
Dosage For Moderate-to-Severe Alzheimer’s Disease
Adult: 10mg taken once at bedtime. Your doctor may increase dosage as needed, but dosage should not exceed 23 mg.
Interactions Of Donepezil
The following are a few of the most common medications and types of medications known to interact with donepezil.
Donepezil raises the levels of a chemical known as acetylcholine in the brain. Anticholinergic medications, however, do the opposite. Therefore, it is not advisable to take donepezil with these types of medications.
Beta blockers are medications that are used to lower blood pressure and slow heart rate. If you take donepezil in conjunction with a beta blocker, there is a chance your heart rate will slow to a dangerously low level.
Certain Heart Rhythm Medications
Some medications known to affect the heart’s rhythm may cause negative interactions with donepezil. These medications include, but are not limited to, the following:
Donepezil Brand Name, Interactions, Dosage And Pronunciation: Summary
Donepezil is a prescription medication that belongs to a class of drugs known as cholinesterase inhibitors. It can be used to treat Alzheimer’s disease and improve mental function and memory in patients.