Emtricitabine-Tenofovir (em tri SIT uh bean; te NOE fo veer) is 2 antiretroviral medicines in 1 tablet. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others. This medicine can also be used with safe sex practices to prevent HIV infection in high-risk persons.