Drosprirenone-ETH Estradiol (dro SPY re nown; ETH in il es tra DYE ole) prevents ovulation and pregnancy. It may also be used to treat acne and premenstrual dysphoric disorder (PMDD). It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.