Metoclopramide Brand Name, Uses, Dosage, Side Effects & Interactions

Metoclopramide is a prokinetic agent which works to increase movement in the stomach and intestines. In doing so, it can help relieve acid reflux and GERD, as well as treat gastroparesis in diabetic patients. In the following short article, we discuss the brand name, uses, side effects, warnings and interactions of metoclopramide.

Metoclopramide Brand Name 

The brand name drugs of metoclopramide include Reglan and Metozolv ODT. Metoclopramide is also available as a generic drug. 

How Does Metoclopramide Work? 

Metoclopramide works by increasing movements and contractions of the stomach and intestines. In doing so, it helps to prevent stomach contents from resurfacing into the esophagus, which often results in acid reflux and heartburn. 

Metoclopramide Uses

Metoclopramide is used to relieve heartburn and accelerate healing of ulcers and sores that appear in the esophagus. For those suffering from gastroesophageal reflux disease (GERD), metoclopramide can help reduce heartburn, especially in cases in which other treatments have not been effective. Metoclopramide is also used to relieve symptoms in patients with diabetes. These symptoms may include vomiting, nausea, heartburn, and loss of appetite. 

Metoclopramide is also used to symptoms of slow stomach emptying (gastroparesis) in patients with diabetes. 

Metoclopramide Side Effects

Metoclopramide does have some associated side effects. Some side effects are more serious and less common than others.

Common Side Effects

Common side effects of metoclopramide include the following:

  • Headache
  • Confusion
  • Dizziness
  • Trouble sleeping
  • Chills
  • Fever
  • Sore throat
  • Nausea
  • Vomiting
  • Increased sweating
  • Increase in blood pressure
  • Lip smacking or puckering

If these side effects are mild, they may disappear within a few days. If you have stopped taking your medication and the effects are still present, talk with your doctor or pharmacist.

Serious Side Effects

If you are experiencing any of the following serious side effects of metoclopramide, contact your doctor or pharmacist immediately. Call 911 if you think your symptoms are life threatening. 

  • Confusion
  • Depression
  • Suicidal Thoughts
  • Seizure
  • Anxiety
  • Rapid weight gain
  • Swelling
  • Severe nervous system reaction (sweating, twitching, rapid heartbeat) 

Disclaimer: Here at Manifest Pharmacy, our goal is to provide you with the most relevant and current information.  However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who  knows your medical history. 

Metoclopramide Dosage

Your dosage for metoclopramide may depend on many factors, including the following: 

  • Your age
  • Your weight
  • Strength of dosage
  • Severity of condition

Dosage For Diabetic Gastroparesis

Adults: At first, 10 mg four times a day, taken 30 minutes before each meal. Dosage should continue for 2 to 8 weeks.Your doctor may adjust dosage as needed. Dosage should not exceed 40 mg per day. 

Dosage For Gastroesophageal Reflux Disease (GERD)

Adults: At first, 10-15 mg four times a day, taken 30 minutes before each meal. Dosage should continue for 4 to 12 weeks. Your doctor may adjust dosage as needed. Dosage should not exceed 60 mg per day. 

What Are The Warnings of Metoclopramide?  

Taking metoclopramide can increase your risk of developing a muscle problem known as dyskinesia. Dyskinesia can result in strange, uncontrollable muscle movements. Notify your doctor immediately if you believe you are at risk for or are experiencing dyskinesia. Call your doctor immediately if you develop any uncontrollable movements, including lip smacking, mouth puckering, frowning, scowling, chewing, blinking, or shaking of the arms and legs. 

Metoclopramide Interactions

Metoclopramide should not be taken in conjunction with any of the following medications: 

  • Antipsychotic drugs, such as aripiprazole and haloperidol.
  • Dopamine agonists, such as cabergoline, pergolide, ropinirole. 
  • MAO inhibitors, such as linezolid, metaxalone, and phenelzine.

Metoclopramide Summary

Metoclopramide is a prokinetic agent which works to increase movement in the stomach and intestines. In doing so, it can help relieve acid reflux and GERD, as well as treat gastroparesis in diabetic patients. 

Metoclopramide can be purchased as the brand name drugs Reglan and Metozolv ODT. It can be used to treat a multitude of conditions, including GERD, acid reflux, gastroparesis, heartburn, and ulcers in the esophagus. 

Metoclopramide

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